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Graduate Students                                                                 

 

Mark Maupin

M.S., Interdisciplinary Masters Program,
B.S., Chemistry Emphasis in Biochemistry,
Boise State University, and
Ph.D., Chemistry, University of Utah

 

Bio:

Christopher Mark Maupin received his Ph.D. under the direction of Greg Voth in December, 2007. His research within the group focuses primarily on Proton Translocation across the Enzyme Active Site for the fully Solvated Carbonic Anhydrase II Enzyme, in both the Dehydration and Hydration Directions.

Latest Publications

C. M. Maupin, and G. A. Voth, "Proton Transport in Carbonic Anhydrase: Insights from Molecular Simulations", BBA - Proteins and Proteomics
(in press). DOI: 10.1016/j.bbapap.2009.09.006 (Invited Review for a Special Issue on Carbonic Anhydrase and Esterase).

C. M. Maupin
, J. Zheng, C. Tu, R. McKenna, D. N. Silverman, and G. A. Voth, "Effect of Active-site Mutations at Asn67 on the Proton Transfer Mechanism of Human Carboic Anhydrase II", Biochemistry 48, 7996-8005 (2009). DOI: 10.1021/bi901037u

C. M. Maupin
, R. McKenna, D. N. Silverman, and G. A. Voth, "Elucidation of the Proton Transport Mechanism in Human Carbonic Anhydrase II", J. Am. Chem. Soc. 131, 7598-7608 (2009). DOI: 10.1021/ja80919358

C. M. Maupin
, M. G. Saunders, I. F. Thorpe, R. McKenna, D. N. Silverman, and G. A. Voth, "Origins of Enhanced Proton Transfer in the Y7F Mutant of Human Carbonic Anhydrase II", J. Am. Chem. Soc. 130, 11399-11408 (2008). DOI: 10.1021/ja802264j

C. M. Maupin, and G. A. Voth, "Preferred Orientation of His-64 in Human Carbonic Anhydrase II", Biochemistry 46, 2938-2947 (2007).
DOI: 10.1021/bi062170f

S. Z. Fisher*, C. M. Maupin*
, L. Govindasamy, M. Budayova-Spano, C. Tu, M. Agbandje-McKenna, D. N. Silverman, G. A. Voth, and R. McKenna, "Atomic Crystal and Molecular Dynamics Simulation Structures of Human Carbonic Anhydrase II: Insights into the Proton Transfer Mechanism", Biochemistry 46, 2930-2937 (2007). ( *SZF and CMM contributed equally to this work). DOI: 10.1021/bi062066y

J. M. J. Swanson, C. M. Maupin*, H. Chen, M. K. Petersen, J. Xu, Y. Wu, and G. A. Voth, "Proton Solvation and Transport in Aqueous and Biomolecular Systems: Insights from Computer Simulations", (Invited Feature Article) J. Phys. Chem. B 111, 4300-4314 (2007).
DOI: 10.1021/jp070104x *Cover Art
for this issue created by C. M. Maupin, and depicts various research projects within the Voth group.

C. M. Maupin
, K. F. Wong, A. V. Soudakov, S. Kim, and G. A. Voth, "A Multi-State Empirical Valence Bond Description of Protonable Amino Acids", J. Phys. Chem. A 110*, 631-639 (2006). *Special Issue: Donald G. Truhlar Festschrift. DOI: 10.1021/jp053596r

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